PUBLICATIONS

PEER REVIEWED

Tan C, Ginzberg MB, Webster R, Iyengar S, Liu S, Papadopoli D, Concannon J, Wang Y, Auld DS, Jenkins JL, Rost H, Topisirovic I, Hilfinger A, Derry WB, Patel N, Kafri R. Cell size homeostasis is maintained by CDK4-dependent activation of p38 MAPK. Dev Cell. 2021 Jun 21;56(12):1756-1769.e7. PMID: 34022133
Francisco MA, Wanggou S, Fan JJ, Dong W, Chen X, Momin A, Abeysundara N, Min HK, Chan J, McAdam R, Sia M, Pusong RJ, Liu S, Patel N, Ramaswamy V, Kijima N, Wang LY, Song Y, Kafri R, Taylor MD, Li X, Huang X. Chloride intracellular channel 1 cooperates with potassium channel EAG2 to promote medulloblastoma growth. J Exp Med. 2020 May 4;217(5):e20190971. PMID: 32097463
Demian WL, Persaud A, Jiang C, Coyaud É, Liu S, Kapus A, Kafri R, Raught B, Rotin D. The Ion Transporter NKCC1 Links Cell Volume to Cell Mass Regulation by Suppressing mTORC1. Cell Rep. 2019 May 7;27(6):1886-1896.e6. PMID: 31067471.
Anzi S, Stolovich-Rain M, Klochendler A, Fridlich O, Helman A, Paz-Sonnenfeld A, Avni-Magen N, Kaufman E, Ginzberg MB, Snider D, Ray S, Brecht M, Holmes MM, Meir K, Avivi A, Shams I, Berkowitz A, Shapiro AMJ, Glaser B, Ben-Sasson S, Kafri R, Dor Y. Postnatal Exocrine Pancreas Growth by Cellular Hypertrophy Correlates with a Shorter Lifespan in Mammals. Dev Cell. 2018 Jun 18;45(6):726-737.e3. PMID: 29920277.
Ginzberg MB, Chang N, D'Souza H, Patel N, Kafri R, Kirschner MW. Cell size sensing in animal cells coordinates anabolic growth rates and cell cycle progression to maintain cell size uniformity. ELife 2018 June PMID: 29889021 (Co-correponding author)
Liu S, Ginzberg MB, Patel N, Hild M, Leung B, Li Z, Chen YC, Chang N, Wang Y, Tan C, Diena S, Trimble W, Wasserman L, Jenkins JL, Kirschner MW, Kafri R. Size uniformity of animal cells is actively maintained by a p38 MAPK-dependent regulation of G1-length. ELife 2018 March PMID: 29595474
Ginzberg M, Kafri R, Kirschner MW. On being the right (cell) size. Science 2015: 348(6236):1245075. PMID: 25977557.

Kafri R, Levy J, Ginzberg MB, Oh S, Lahav G, Kirschner MW. Dynamics extracted from fixed cells reveal feedback linking cell growth to cell cycle. Nature 2013: 494 (7438): 480-3. PMID: 23446419

Karanam K, Kafri R (equal contribution with Karanam), Löwer A, Lahav G. Quantitative live cell imaging reveals a gradual shift between DNA repair mechanisms and a maximal use of HR in mid S phase. Mol. Cell 2012: 47 (2): 320-9. PMID: 22841003

Jain M, Nilsson R, Sharma S, Madhusudhan N, Kitami T, Souza AL, Kafri R, Kirschner MW, Clish CB, Mootha VK. Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation. Science 2012: 336 (6084): 1040-4. PMID: 22628656

Juang YT, Peoples C, Kafri R, Kyttaris VC, Sunahori K, Kis-Toth K, Fitzgerald L, Ergin S, Finnell M, Tsokos GC. A systemic lupus erythematosus gene expression array in disease diagnosis and classification: a preliminary report. Lupus 2011: 20 (3): 243-9. PMID: 21138984

Kafri R, Markovitch O, Lancet D. Spontaneous chiral symmetry breaking in early molecular networks. Biol. Direct 2010: 5: 38. PMID: 20507625

Tzur A, Kafri R (equal contribution with Tzur), LeBleu VS, Lahav G, Kirschner MW. Cell growth and size homeostasis in proliferating animal cells. Science 2009: 325 (5937): 167-71. PMID: 19589995

Kafri R, Springer M, Pilpel Y. Genetic redundancy: new tricks for old genes. Cell 2009: 136 (3): 389-92. PMID: 19203571

Kafri R, Dahan O, Levy J, Pilpel Y. Preferential protection of protein interaction network hubs in yeast: evolved functionality of genetic redundancy. Proc. Natl. Acad. Sci. 2008: 105 (4): 1243-8. PMID: 18216251

Kafri R, Levy M, Pilpel Y. The regulatory utilization of genetic redundancy through responsive backup circuits Proc. Natl. Acad. Sci. 2006: 103 (31): 11653-8. PMID: 16861297

Shenhav B, Bar-Even A, Kafri R, Lancet D. Polymer GARD: computer simulation of covalent bond formation in reproducing molecular assemblies. Orig. Life Evol. Biosph. 2005: 35 (2): 111-33. PMID: 16010993

Kafri R, Bar-Even A, Pilpel Y. Transcription control reprogramming in genetic backup circuits. Nat. Genet. 2005: 37 (3): 295-9. PMID: 15723064

Kafri R, Lancet D. Probability rule for chiral recognition. Chirality 2004: 16: 369-78. PMID: 15190582

Rosenwald S, Kafri R, Lancet D. Test of a statistical model for molecular recognition in biological repertoires. J. Theor. Biol. 2002: 216 (3): 327-36. PMID: 12183121

Segré D, Shenhav B, Kafri R, Lancet D. The molecular roots of compositional inheritance. J. Theor. Biol. 2001: 213 (3): 481-91. PMID: 11735293

Kolusheva S, Kafri R, Katz M, Jelinek R. Rapid colorimetric detection of antibody-epitope recognition at a biomimetic membrane interface. J. Am. Chem. Soc. 2001: 123 (3): 417-22. PMID: 11456543

INVITED REVIEWS AND BOOK CHAPTER

Kafri R, Pilpel Y. Evolutionary and Functional Aspects of Genetic Redundancy. Evolution After Gene Duplication; Dittmar K, Liberles D (Editors), Wiley-Blackwell, 2010.

Toronto Lab of Cell Size
Investigating mechanisms of cellular identity

PUBLICATIONS

PEER REVIEWED

Demian WL, Persaud A, Jiang C, Coyaud É, Liu S, Kapus A, Kafri R, Raught B, Rotin D. The Ion Transporter NKCC1 Links Cell Volume to Cell Mass Regulation by Suppressing mTORC1. Cell Rep. 2019 May 7;27(6):1886-1896.e6. PMID: 31067471.

Ginzberg MB, Chang N, D'Souza H, Patel N, Kafri R, Kirschner MW. Cell size sensing in animal cells coordinates anabolic growth rates and cell cycle progression to maintain cell size uniformity. ELife 2018 June PMID: 29889021 (Co-correponding author)

Liu S, Ginzberg MB, Patel N, Hild M, Leung B, Li Z, Chen YC, Chang N, Wang Y, Tan C, Diena S, Trimble W, Wasserman L, Jenkins JL, Kirschner MW, Kafri R. Size uniformity of animal cells is actively maintained by a p38 MAPK-dependent regulation of G1-length. ELife 2018 March PMID: 29595474

Ginzberg M, Kafri R, Kirschner MW. On being the right (cell) size. Science 2015: 348(6236):1245075. PMID: 25977557.

Kafri R, Levy J, Ginzberg MB, Oh S, Lahav G, Kirschner MW. Dynamics extracted from fixed cells reveal feedback linking cell growth to cell cycle. Nature 2013: 494 (7438): 480-3. PMID: 23446419

Karanam K, Kafri R (equal contribution with Karanam), Löwer A, Lahav G. Quantitative live cell imaging reveals a gradual shift between DNA repair mechanisms and a maximal use of HR in mid S phase. Mol. Cell 2012: 47 (2): 320-9. PMID: 22841003

Jain M, Nilsson R, Sharma S, Madhusudhan N, Kitami T, Souza AL, Kafri R, Kirschner MW, Clish CB, Mootha VK. Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation. Science 2012: 336 (6084): 1040-4. PMID: 22628656

Juang YT, Peoples C, Kafri R, Kyttaris VC, Sunahori K, Kis-Toth K, Fitzgerald L, Ergin S, Finnell M, Tsokos GC. A systemic lupus erythematosus gene expression array in disease diagnosis and classification: a preliminary report. Lupus 2011: 20 (3): 243-9. PMID: 21138984

Kafri R, Markovitch O, Lancet D. Spontaneous chiral symmetry breaking in early molecular networks. Biol. Direct 2010: 5: 38. PMID: 20507625

Tzur A, Kafri R (equal contribution with Tzur), LeBleu VS, Lahav G, Kirschner MW. Cell growth and size homeostasis in proliferating animal cells. Science 2009: 325 (5937): 167-71. PMID: 19589995

Kafri R, Springer M, Pilpel Y. Genetic redundancy: new tricks for old genes. Cell 2009: 136 (3): 389-92. PMID: 19203571

Kafri R, Dahan O, Levy J, Pilpel Y. Preferential protection of protein interaction network hubs in yeast: evolved functionality of genetic redundancy. Proc. Natl. Acad. Sci. 2008: 105 (4): 1243-8. PMID: 18216251

Kafri R, Levy M, Pilpel Y. The regulatory utilization of genetic redundancy through responsive backup circuits Proc. Natl. Acad. Sci. 2006: 103 (31): 11653-8. PMID: 16861297

Shenhav B, Bar-Even A, Kafri R, Lancet D. Polymer GARD: computer simulation of covalent bond formation in reproducing molecular assemblies. Orig. Life Evol. Biosph. 2005: 35 (2): 111-33. PMID: 16010993

Kafri R, Bar-Even A, Pilpel Y. Transcription control reprogramming in genetic backup circuits. Nat. Genet. 2005: 37 (3): 295-9. PMID: 15723064

Kafri R, Lancet D. Probability rule for chiral recognition. Chirality 2004: 16: 369-78. PMID: 15190582

Rosenwald S, Kafri R, Lancet D. Test of a statistical model for molecular recognition in biological repertoires. J. Theor. Biol. 2002: 216 (3): 327-36. PMID: 12183121

Segré D, Shenhav B, Kafri R, Lancet D. The molecular roots of compositional inheritance. J. Theor. Biol. 2001: 213 (3): 481-91. PMID: 11735293

Kolusheva S, Kafri R, Katz M, Jelinek R. Rapid colorimetric detection of antibody-epitope recognition at a biomimetic membrane interface. J. Am. Chem. Soc. 2001: 123 (3): 417-22. PMID: 11456543

INVITED REVIEWS AND BOOK CHAPTER

Kafri R, Pilpel Y. Evolutionary and Functional Aspects of Genetic Redundancy. Evolution After Gene Duplication; Dittmar K, Liberles D (Editors), Wiley-Blackwell, 2010.

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